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Thursday, July 30, 2020 | History

2 edition of Mechanism of intoxication of DDT insecticides in insects and warm-blooded animals found in the catalog.

Mechanism of intoxication of DDT insecticides in insects and warm-blooded animals

Paul LaМ€uger

Mechanism of intoxication of DDT insecticides in insects and warm-blooded animals

by Paul LaМ€uger

  • 219 Want to read
  • 37 Currently reading

Published by Geigy company, inc. in [New York .
Written in English

    Subjects:
  • DDT (Insecticide)

  • Edition Notes

    Statementpresented at the joint meeting of the Army committee for insect and rodent control and the OSRD Insect control committee by Dr. Paul Läuger.
    ContributionsGeigy Company.
    Classifications
    LC ClassificationsRA1242.D35 L3
    The Physical Object
    Pagination24 p. incl. tables, diagrs.
    Number of Pages24
    ID Numbers
    Open LibraryOL6497128M
    LC Control Number46003419
    OCLC/WorldCa3640224

      Pesticides include several classes such as insecticides, herbicides, fungicides, and have widespread usage in agriculture. Different type of pesticides and their combinations affect dairy animals through their lifetime and the livestock industry. Under chronic exposure conditions, hormonal and cellular systems of animals, which play a role in reproduction, are affected dramatically.   A single genetic mutation causes resistance to DDT and pyrethroids (an insecticide class used in mosquito nets), according to new research in the journal Genome resistance to pyrethroids and DDT is already spreading in mosquito populations, scientists say that this knowledge could help improve malaria control strategies.

      Introduction DDT is good for me advertisement, Time, J Scan by Flickr user Crossett ve Commons license CC BY-NC-SA Early in , Dottie Colson wrote to the National Health Council in New York City for advice on how to start a "real health movement" in her hometown. Colson believed that use of the pesticide DDT in her rural community outside of Claxton, .   Since the overall shapes and sizes of DDT and DDD are similar, their toxicity to insects is as well. In the past, DDD was itself sold as an insecticide, but it has also been discontinued because it bioaccumulates. Notice that DDE, unlike DDT and DDD, is based upon a planar C=C unit rather than a C—C linkage which has tetrahedral groups at.

      It's why we give away ACSH coffee mugs with relative toxicity on them (See Note 1, below). The following table compares DDT's acute oral toxicity in several animal species to that of common substances. The measurement used to determine toxicity is LD 50 the dose required to kill half of the test animals. the fact that DDT has extremely low toxicity for most warm-blooded animals and is one of the most safe and most effective insecticides. Probably no antibiotic saved so many people from unnecessary and avoidable death as did DDT, through its use in the fightagainst malaria. The campaign against DDT has no rational ex-planation.


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Mechanism of intoxication of DDT insecticides in insects and warm-blooded animals by Paul LaМ€uger Download PDF EPUB FB2

Book: Mechanism of Intoxication of DDT Insecticides In Insects and warmblooded Animals. pp pp. ref.5 Abstract: From previous work, the authors concluded that the contact action of DDT ddt Subject Category: Chemicals and Chemical GroupsCited by: 2.

Author(s): Läuger,Paul, Title(s): Mechanism of intoxication of DDT insecticides in insects and warm-blooded animals, presented at the joint meeting of the Army committee for insect and rodent control of the OSRD Insect control committeeby Dr.

Paul Läuger. The mechanism by which DDT acts is to disturb the function of nerves in the insect. Nerves in both insects and humans work by allowing an electric current to move down them. This action potential, as it is called, depends on the movement of two metal ions, sodium and potassium, across the membrane of the nerve, and involves channels for the.

Insects with certain mutations in their sodium channel gene are resistant to DDT and similar insecticides. DDT resistance is also conferred by up-regulation of genes expressing cytochrome P in some insect species, [23] as greater quantities of some enzymes of this group accelerate the toxin's metabolism into inactive al formula: C₁₄H₉Cl₅.

DDT is still effectively used for malaria control in several third world countries. InDr. Paul Muller, a Swiss entomologist, was awarded the Nobel Prize in Medicine for his lifesaving discovery of DDT () as an insecticide useful in the control of malaria, yellow fever and many other insect.

The toxicity of DDT applied externally is low to all mammals; however, it shows a great variation of effectiveness with species toward insects. When DDT is applied to isolated tissues and enzymes, only nervous tissue is sensitive to very low concentrations.

DDT is. Insecticides plays a pivotal role in pest management, Mode of action of insecticides is very important toxicological aspects to be clearly understood to develop a strategic plan against pests.

Mechanism of intoxication of DDT insecticides in insects and warm-blooded animals. Mortality of bed bugs on rabbits given oral dosages of DDT & pyrethrum. DDT toxicity. A report on the toxicity to warm-blooded animals of aerosols.

DDT is one of the most controversial chemical compounds in recent history. It has proven effective as an insecticide, but its potent toxicity isn't limited to by many countries including the United States, DDT is nonetheless still used—legally or illegally—in some places.

W.-T. Tsai, in Encyclopedia of Toxicology (Third Edition), Abstract. Organochlorine insecticides are chlorinated hydrocarbons to control insects and insect-borne diseases. However, they are often capable of persisting in the environment, transporting between phase media and accumulating to levels, implying that they could pose a risk of causing adverse effects to human health and the.

Fipronil and dieldrin are known to inhibit GABA receptors in both mammals and insects. However, the mechanism of selective toxicity of these insecticides between mammals and insects remains to be. Mechanism of the Toxic Action of DDT, with Reference to Cholinesterase Systems in Higher Animals and Insects.

Foreign Title: Contribution a 1'étude du mécanisme de 1'action toxique de 1'insecticide D.D.T. D.D.T. et systèmes cholinestérasiques chez les animaux supérieurs et les insectes.

Paul Hermann Müller, (born Jan. 12,Olten, Switz.—died Oct. 12,Basel), Swiss chemist who received the Nobel Prize for Physiology or Medicine in for discovering the potent toxic effects on insects of its chemical derivatives, DDT became the most widely used insecticide for more than 20 years and was a major factor in increased world food production and the.

To survive the natural toxins, insects have evolved various detoxification mechanisms. These same mechanisms also sometimes allow insects to overcome insecticides, and the level and type of mechanisms differ greatly. This results in differing toxicity among different stages, populations, and species of insects.

The LCso of DDT and'DDE for Various Birds* DDT(ppm) Mallards Pheasants Bobwhites Cotumix to to to to 1, 1, DDE(ppm) 3, 1, to to to to 3, 1, * Insecticides in diets of two-week-old birds when fed treated feed for five days followed by untreated feed for three days Pheasants were.

The organic chlorine insecticides were inexpensive to produce, nonvolatile, environmentally stable, and had relatively low acute toxicity when compared to previous insecticides.

Most organic chlorines have a negative temperature coefficient, making them more insecticidal at lower temperatures and less toxic to warm-blooded. 40 CHAPTER 4 Pyrethrins & Pyrethroids sures, followed by depolarization, conduction block and cell death at very high levels of exposure.7 In addition to the calcium and sodium channel sites of action, multiple other sites described include GABA receptors (for Type II effects, see following).

If there is a single pesticide almost everyone can name, it's DDT. DDT was one of the first chemicals in widespread use as a pesticide. Following World War II, it was promoted as a wonder-chemical, the simple solution to pest problems large and small. Today, nearly 40 years after DDT was banned in the U.S., we continue to live with its long-lasting effects: Food supplies: USDA.

and its very high toxicity to warm-blooded animals until it was banned according to the Montreal Protocol (Dansi et al., ). Phosphine remains one of the most commonly used insecticides. In parallel, carbon dioxide is an important element enhancing the efficacy of controlled atmosphere treatments aimed at increasing pest mortality (Wang et al.

DDT is one of the most effective pesticides ever discovered for fighting malaria. Although DDT remains legal for insecticide use in most areas where malaria is a major killer, the money for fighting the mosquitos often comes from donors in wealthy countries like the United States.

Moreover, some formulations contain additional insecticides, insect repellents, and solvents such as alcohol and petroleum, which increase pesticide toxicity.

Triazines basically consist of herbicide compounds, are relatively persistent and migrate easily .The hazard of DDT to nontarget animals is particularly acute for those species living at the top of food chains.

Link to discussion of how DDT becomes concentrated as it moves up a food chain. Carnivores at the ends of long food chains (e.g., ospreys, pelicans, falcons, and eagles) once suffered serious declines in fecundity and hence in.DDT and Birds.

Birds played a major role in creating awareness of pollutionmany people consider the modern environmental movement to have started with the publication in of Rachel Carson's classic Silent Spring, which described the results of the misuse of DDT .